'工学部/工学系研究科 トピックス' blog (64135253074) of hub id 20511701

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Akinobu Sendo (D2), Department of Chemistry and Biotechnology, won the Young Scientist Excellence Award, EMBO reports Young Scientist Award of Excellence at the 19th Protein

 

On 25th June 2019, Akinobu Sendo (D2), Department of Chemistry and Biotechnology, won the Young Scientist Excellence Award, EMBO reports Young Scientist Award of Excellence at the 19th Protein Science Society of Japan.

 

 

< About awarded research>
Title: Structural insight into inhibition of homophilic dimerization mediated by cell adhesion protein P-cadherin utilizing a small molecule ligand

 

P-cadherin is a cell adhesion protein expressed in cancer cells. This protein is related to cancer metastasis, so a molecular targeting drug to inhibit the function of P-cadherin is in high demand. In our research, we identified a small molecule regulator of P-cadherin function for the first time in the world and elucidated its inhibitory mechanism using X-ray crystal structure analysis.

<your impression & future plan>
It is such an honor to be awarded this prize. I thank all the conference staff and Prof. Tsumoto and members in our laboratory.