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2019.05.10

【Awards and Commendations】Kensaku Matsunami(D2), Associate Professor Hirokazu Sugiyama, Department of Chemical System Engineering, and other researchers received the Technical Achievement Award of the Division of Systems, Information and Simulation Technologies (SIS) at The Society of Chemical Engineers, Japan 84th Annual Meeting.

Kensaku Matsunami(D2), Associate Professor Hirokazu Sugiyama, Department of Chemical System Engineering, and other researchers received the Technical Achievement Award of the Division of Systems, Information and Simulation Technologies (SIS) at The Society of Chemical Engineers, Japan 84th Annual Meeting.

Title: Economic evaluation of solid drug product manufacturing processes considering continuous manufacturing

Authors: Kensaku Matsunami, Shuichi Tanabe, Keita Yaginuma, Hirokazu Sugiyama
             Co-awardee from Daiich Sankyo: Dr. Shuichi Tanabe, Mr. Keita Yaginuma

Summary: Designing pharmaceutical manufacturing processes is extremely difficult because it is done during clinical development when there is high uncertainty and appropriate process depends on products. In addition, the fact that continuous manufacturing is now becoming a new alternative makes design problems even more complicated. We presented an economic evaluation of manufacturing processes considering continuous manufacturing for solid drug products such as tablets and capsules. Also, we demonstrated a software tool which we developed for supporting decision making in the real process design. This work enabled comprehensive alternative generation and economic evaluation considering uncertainty, furthermore, can contribute to smooth development and launch of new drugs.

 

It is our pleasure to receive this award. We deeply appreciate the collaborators and the members of Hirao-Sugiyama laboratory. We will continue to work on the topic for extending the research and implementing the outcome in the real world.