25th July 2024, Keisuke Kasahara (D3) , Tsumoto Lab, Department of Bioengineering, recieved Graduate Student Poster Competition Award at The 38th Annual Symposium of the Protein Society.
The 38th Annual Symposium of the Protein Society Graduate Student Poster Competition Award
This award is conferred for excellent poster presentations delivered by graduate students.
About awarded research
Title: Fc-supercharging to enhance the adsorption and control the orientation of antibodies to the cellulose nanoparticles
In this research, we aimed to improve the antibody adsorption state on nanoparticles through surface charge engineering of proteins, known as “supercharging.” We confirmed the structure and physicochemical properties of Fc-supercharged IgG mutants and succeeded in enhancing the sensitivity of the lateral flow immunoassay (LFI). LFI is widely used in applications such as antigen tests and pregnancy tests. Therefore, improvements in the sensitivity of LFI and ease of producing test kits are anticipated.
Your impression & future plan
I am honored to receive this award. I appreciate Professor Kouhei Tsumoto, Dr. Satoru Nagatoishi, and Dr. Daisuke Kuroda for all their advice and support. This research was conducted in collaboration with Asahi Kasei Corporation, and LFI with cellulose nanoparticles was evaluated by Mr. Junichi Sato, Mr. Keisuke Murakami, and Dr. Hirokazu Nagai. I want to express my sincere gratitude to them. I am eager to continue advancing my research.