Minimally invasive bone implant made possible ｰDevelopment of novel artificial bone with excellent bone-forming abilityｰ ： Professor Yuichi Tei/Ung-il Chung, Department of Bioengineering
May 16, 2014
The University of Tokyo research group including Professor Yuichi Tei/Ung-il Chung, Department of Bioengineering, Graduate Schools of Engineering and Medicine, Professor Manabu Mochizuki, Veterinary Medical Center, Graduate School of Agriculture and Life Sciences, and President Shigeki Suzuki, NEXT21 K.K. successfully developed novel artificial bone with high bone-forming ability and easy operability. This artificial bone is made of low crystallinity octa-calcium phosphate (OCP) by injection molding. Swedish research group at Department of Biomaterials, University of Gothenburg tested this novel artificial bone in comparison with processed bovine bone to prove its excellence in bone formation, fusion and replacement abilities.
Because this artificial bone is made by injection molding, given shape can be formed. OCP formation after molding enables fabrication of OCP artificial bone for the first time. This novel artificial bone is similar in shape and component to deproteinized cadaver bone (allograft) and processed bovine bone (xenograft).
In Japan, allograft is not popular and bone bank is not available. Therefore, autograft obtained from healthy sites including iliac bone and fibula is widely used instead. This new artificial bone made of OCP by injection molding may enable a new type of bone transplant not relying on autograft or bone-bank-derived allograft. Furthermore, it will help reduce surgical burden of autograft.